Showing posts with label inherited. Show all posts
Showing posts with label inherited. Show all posts

Saturday 6 February 2016

Gremlin gene associated with Hypodontia ! Yes Gremlin !

As a child of the 80's I loved the Gremlins films as well as Back to the Future Indiana Jones etc. So it turns out that there is a Bone Morphogenic Protein antagonist that is known to regulate BMPs in embryogenesis and tissue development. Have a look at the abstract of some research by a group from Thailand.  

Gremlin 2 BMP

Friday 8 January 2016

Certain genes are related to certain patterns of missing teeth

I could never profess to knowing anything about genetics in any great detail ! In this graphic the two main genes in Hypodontia are illustrated. MSX1 shows a significantly different pattern of tooth loss to PAX9 which is heavily associated with the commonly missing lateral incisors and premolars. Have a read of the below article for more information.