Showing posts with label inherited condition. Show all posts
Showing posts with label inherited condition. Show all posts

Saturday 6 February 2016

Gremlin gene associated with Hypodontia ! Yes Gremlin !

As a child of the 80's I loved the Gremlins films as well as Back to the Future Indiana Jones etc. So it turns out that there is a Bone Morphogenic Protein antagonist that is known to regulate BMPs in embryogenesis and tissue development. Have a look at the abstract of some research by a group from Thailand.  

Gremlin 2 BMP

Friday 8 January 2016

Certain genes are related to certain patterns of missing teeth

I could never profess to knowing anything about genetics in any great detail ! In this graphic the two main genes in Hypodontia are illustrated. MSX1 shows a significantly different pattern of tooth loss to PAX9 which is heavily associated with the commonly missing lateral incisors and premolars. Have a read of the below article for more information.  





Saturday 24 October 2015

Is hypodontia a wholly genetic condition ?

An article in the British Dental Journal from 2007 reviews current knowledge on the aetiological basis for hypodontia as well as various types of presentation and classification. Syndromes that are associated with congenitally missing teeth are also illustrated in a table. Click on the link below for the full article. 

Hypodontia-Is it all in the genes ?